Effect of oleanolic acid (OA) on expressions of SODs in chronic CsA nephropathy. (A) Immunoblotting for the target molecules of SOD1 and SOD2 showing the effects of OA in chronic CsA nephropathy. (B) Quantitative analyses for SOD1/β-actin. The expression of SOD1 was significantly decreased in CsA but increased in CsA + OA mice. *p <0.05 vs. other groups. (C) Quantitative analyses for SOD2/β-actin. There were no significant differences in the expression of SOD2 among the experimental groups. SOD = superoxide dismutase; VH = vehicle-treated group; VH + OA = vehicle plus oleanolic acid-treated group; CsA = cyclosporine-treated group; CsA + OA = cyclosporine plus oleanolic acid-treated group.