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Table 5 IHC analysis of subcutaneous or intraperitoneal plg injection treatment for TM perforations in WT mice

From: Plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice

Treatment group

Healed TM perforations/Total TM perforations

Subcutaneous PBS injection

3/10 (30%)

Subcutaneous plg injection

5/10 (50%)

P value

0.36131

Intraperitoneal PBS injection

3/10 (30%)

Intraperitoneal plg injection

5/10 (50%)

P value

0.36131

  1. Data were analyzed at day 8 after the perforations. The healing rate was calculated and is shown in parentheses.