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Table 3 Otomicroscopical and IHC analysis of local plg injection treatment for TM perforations in WT mice

From: Plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice

Treatment

Otomicroscopical analysis

IHC analysis

Day 4

Day 5

Day 6

Day 7

Day 7

Plg-treated

0/21

3/21

8/21

13/21

13/21

(0%)

(14%)

(38%)

(62%)

(62%)

PBS-treated

0/12

0/12

1/12

3/12

1/12

(0%)

(0%)

(8%)

(25%)

(8%)

P value

N/A

0.169686

0.064794

0.041292$

0.002741$

  1. The closure rate was calculated and is shown in parentheses. $ P < 0.05.