From: Plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice
Treatment group
Healed TM perforations/Total TM perforations
Plg-/- mice
Group 1 (0.4 mg/day)
10/10 (100%)
Group 2 (0.2 mg/day)
Group 3 (0.1 mg/day)
6/10 (60%)
Group 4 (PBS)
0/10 (0%)
WT mice (non-treated)