Effect of FTZ on IRS1 protein expression. The protein expression of IRS1 was detected via western blotting as described in the text. The figure represents one of three experiments with similar results. Lane1, control; Lane2, IR (FTZ 0 μg/ml); Lane3, RGS 10 μmol/l; Lane4, FTZ 100 μg/ml; Lane5, FTZ 25 μg/ml; Lane 6, FTZ 1 μg/ml. ΔP<0.05 compared to the control cells; *P< 0.05 compared to the IR cells.