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Table 2 Mouse characteristics for generation of GIST patient-derived xenografts

From: Generation of orthotopic patient-derived xenografts from gastrointestinal stromal tumor

 

Number

Percent (%)

Age at implantation

  

  Mean ± standard deviation

9.1 ± 7.3 weeks

 

  Range

5.7 – 30.6 weeks

 

Gender

  

  Male

8

32.0%

  Female

17

68.0%

Genotype

  

  NOD-scid (NS)

10

40.0%

  NOD-scid gamma (NSG)

15

60.0%

Tumor development

  

  Yes

21

84.0%

  No

4

16.0%

Passages

  

  0 (Primary, successes/total)

11/14

85.7%

  1 (Successes/total)

5/6

83.3%

  2 (Successes/Total)

5/5

100.0%

Location of implantation

  

  Successful implantations/total

21/25

84.0%

   Liver (successes/total)

9/10

90.0%

   Renal capsule (successes/total)

9/10

90.0%

   Lesser sac (successes/total)

2/3

66.7%

   Gastric wall (successes/total)

1/2

50.0%