Skip to main content

Table 2 Mouse characteristics for generation of GIST patient-derived xenografts

From: Generation of orthotopic patient-derived xenografts from gastrointestinal stromal tumor

  Number Percent (%)
Age at implantation   
  Mean ± standard deviation 9.1 ± 7.3 weeks  
  Range 5.7 – 30.6 weeks  
Gender   
  Male 8 32.0%
  Female 17 68.0%
Genotype   
  NOD-scid (NS) 10 40.0%
  NOD-scid gamma (NSG) 15 60.0%
Tumor development   
  Yes 21 84.0%
  No 4 16.0%
Passages   
  0 (Primary, successes/total) 11/14 85.7%
  1 (Successes/total) 5/6 83.3%
  2 (Successes/Total) 5/5 100.0%
Location of implantation   
  Successful implantations/total 21/25 84.0%
   Liver (successes/total) 9/10 90.0%
   Renal capsule (successes/total) 9/10 90.0%
   Lesser sac (successes/total) 2/3 66.7%
   Gastric wall (successes/total) 1/2 50.0%