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Table 1 Metabolic changes pre and post VA-ECMO resuscitation of hypoxic cardiac arrest

From: Rat model of veno-arterial extracorporeal membrane oxygenation

Biochemical parameter

Baseline

Anoxia

Resuscitation

P

HCO3-, mmol/L (SD)

20.9 (0.8)

14.1 (2.2)*

19.6 (1.8)

<0.001

pH, (SD)

7.49 (0.1)

6.99 (0.1)*

7.38 (0.1)

<0.001

pCO2,, mmHg (SD)

23 (11)

105 (29)*

42 (8)

<0.001

pO2,, mmHg (SD)

225 (37)

64 (17)*

270 (55)

<0.001

Hb, g/dl (SD)

15.5 (1.2)

16.4 (1.1)

9.2 (2.1)*

<0.001

HCT, % (SD)

47 (4)

50 (3)

31 (3)*

<0.001

sO2, % (SD

96 (2)

48 (18)*

99 (3)

<0.001

K+, mmol/l (SD)

3.7 (0.8)*

5.5 (1.0)

5.1 (1.2)

<0.001

Ca+, mmol/l (SD)

2.5 (0.8)

2.4 (0.3)

2.2 (0.4)

0.73

Lactate, mmol/L (SD)

3.3 (0.5)

3.7 (1.1)

2.8 (0.9)

0.43

  1. HCO3-: Bicarbonate; pCO 2: partial pressure of CO2; pO2: partial pressure of O2; Hb: Hemoglobin; HCT: Hematocrit; sO2; K+: Potassium; Ca+: Calcium. Continuous data are presented as mean with 95% confidential intervals (95% CI) or as median with interquartile ranges (IQR 25-75). *Bonferroni’s Multiple Comparison Test.