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Table 1 Body and kidney weights of Sham, 2K1C and 2K1C-sildenafil treated mice 28 days after renal artery clipping

From: Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension

Parameters Sham (n = 8) 2K1C (n = 10) 2K1C sildenafil (n = 8)
Body weight (g) 26 ± 0.5 24 ± 0.4* 26 ± 0.3#
Clipped kidney dry weight/body weight (mg/g) 1.63 ± 0.07 0.96 ± 0.17** 1.5 ± 0.04#
Nonclipped kidney dry weight/body weight (mg/g) 1.78 ± 0.04 2.02 ± 0.06* 1.77 ± 0.05#
Clipped kidney weight/nonclipped kidney weight ratio 0.91 ± 0.04 0.54 ± 0.09** 0.78 ± 0.06#
Kidney cell viability (%) 99 ± 0.13 94 ± 1.5** 98 ± 0.6#
  1. Values are the means ± SEM. *p < 0.05 and **p < 0.01 compared with Sham group; # p < 0.05 compared with 2K1C group.