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Table 2 Clinical data on patients with severe sepsis

From: Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis

Underlying conditions Source of sepsis Organism Renal failure? Respiratory failure?
Lung cancer Pneumonia Blood: E.coli, Strep bovis no yes
Resp: E.coli
Prodrome with nausea and vomiting for 7 days Pneumonia Blood: culture negative no yes
Urine: Legionella antigen positive
ETOH cirrhosis Spontaneous bacterial peritonitis Blood: culture negative no yes
Status/Post gastric bypass Urinary tract infection Blood: E. Coli no yes
Obstructive nephrolithiasis pyelonephritis Urinary tract infection Blood: E.Coli no yes
Urine: E.Coli
End stage renal disease Catheter sepsis Blood: MRSA yes (prior to admission) yes
Acute myelogenous leukemia (relapse) Portacath sepsis Blood: MRSA no yes
Urine: Enterobacter
Influenza Pneumonia with coexistent Influenza A Blood: Strep pneumonia no yes
Resp: Influenza A
Diabetes mellitus Infected diabetic foot ulcer Blood: Staph aureus no yes
Chronic kidney disease Body Fluid: Staph aureus
Gout Resp: MRSA
Head and neck cancer Pneumonia Blood: culture negative no yes
Resp: culture negative
Diabetes mellitus Pneumonia and colitis Blood: culture negative yes (dialysis required) yes
Congestive heart failure
Gastrointestinal hemorrhage
Resp: MRSA
Cellulitis Pneumonia Blood: Group a strep. no no
Hypercholesterolemia Urinary tract infection
Multiple myeloma PneumoniaUrinary tract infection Blood: Gram positive cocci no yes
Urine: Proteus mirabilis
Non-Hodgkins lymphoma Pancreatitis Resp: Aspergillus fumigatus no yes
Bone marrow transplant Intra-abdominal sepsis Blood: Gram negative rods, Gram positive cocci no yes
Bowel perforation
Post allogeneic bone marrow transplant Pneumonia Blood: culture negative no yes
Chronic opiate use Aspiration pneumonia Blood: Strep. pneumonia no yes
Found obtunded Resp: Strep. pneumonia, Candida glabrata
Diabetes mellitus Aspiration pneumonia Resp: Gram negative rods, gram positive cocci yes (prior to admission) yes
End stage renal disease
Chronic obstructive pulmonary disease Pneumonia Blood: culture negative no yes
Resp: Acinetobacter, Stenotrophomonas maltiphilia
Toxic epidermal necrolysis Skin Blood: MRSA yes yes
Acute renal failure
Alcoholic cirrhosis Subacute bacterial peritonitis Blood: culture negative no no
Hepatorenal syndrome
Chronic obstructive pulmonary disease Pneumonia Blood: Gram positive rods no yes
Severe ankylosing spondylitis Urinary tract infection Blood: Klebsiella pneumonia no yes
Urine: Klebsiella pneumonia
Severe aortic stenosis
Hepatitis C cirrhosis Health care acquired pneumonia Blood: culture negative yes (dialysis required) yes
Urine: Enterococcus
Esophageal varicies
Systemic mastocytosis Pneumonia Blood: culture negative no yes
Congestive heart failure Resp: Budding yeast with pseudohyphae