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Table 4 Median mRNA levels for 7 candidate genes in TOF cases and controls

From: Association of promoter methylation statuses of congenital heart defect candidate genes with Tetralogy of Fallot

Gene Gene bank accession Control, median (IQR), N TOF, median (IQR), N mRNA fold change P value
EGFR NM_201282 3.98 (1.84 – 6.93); N = 6 0.61 (0.46 – 0.75); N = 33 0.15 0.0003***
EVC2 NM_001166136 3.95 (1.50 – 6.21); N = 6 0.96 (0.79 – 1.56); N = 32 0.24 0.0033**
NFATC2 NM_001136021 7.72 (4.60 – 11.50); N = 6 1.39 (0.97 – 1.88); N = 41 0.18 0.0043**
NR2F2 NM_021005 3.27 (1.34 – 4.88); N = 6 1.12 (0.70 – 1.30); N = 41 0.34 0.0039**
TBX5 NM_080717 1.49 (1.35 – 4.42);N = 6 0.41 (0.19 – 0.67); N = 37 0.28 0.0013**
CFC1B NM_001079530 2.20 (1.57 – 7.50); N = 6 0.66 (0.31 – 1.07); N = 39 0.30 0.0016**
GJA5 NM_005266 0.77 (0.34 – 1.06); N = 6 0.19 (0.16 – 0.32); N = 36 0.25 0.0053**
  1. **P < 0.01, ***P < 0.001 (Mann–Whitney test), IQR, Interquartile range.