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Figure 9 | Journal of Translational Medicine

Figure 9

From: Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny

Figure 9

The putative therapeutic advantage of m- CRA virotherapy. In general, the therapeutic effectiveness of chemoradiotherapy is decreased in the advanced malignant tumor cells, and in particular, CSCs are resistant to conventional chemoradiotherapies. In contrast, not only m-CRA virotherapy can efficiently kill all populations of malignant tumor cells, including CSCs and their progeny, but also the antitumor effects of m-CRA virotherapy are higher against CSCs.

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