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Table 1 Immune-response response criteria (irRC)

From: Vaccination with autologous dendritic cells loaded with autologous tumor lysate or homogenate combined with immunomodulating radiotherapy and/or preleukapheresis IFN-α in patients with metastatic melanoma: a randomised “proof-of-principle” phase II study

Index lesions

Non-index lesions

New measurable lesions

New non-measurable lesions

% Change in tumor burden

irRC-overall response

CR

CR

No

No

−100%

irCR

PR

Any

Any

Any

≥ -50%

irPR

PR

Any

Any

Any

< -50% to < +25%

irSD

PR

Any

Any

Any

≥ +25%

irPD

SD

Any

Any

Any

< -50% to < +25%

irSD

SD

Any

Any

Any

≥ +25%

irPD

PD

Any

Any

Any

≥ +25%

irPD

SD

Any

Any

Any

< -50% to < +25%

irSD

SD

Any

Any

Any

≥ +25%

irPD

PD

Any

Any

Any

≥ +25%

irPD

  1. irRC: immune-related response criteria; PR: partial response; SD: stable disease; PD: progressive disease.
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Journal of Translational Medicine

ISSN: 1479-5876

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