Figure 6From: Prediction of brain clozapine and norclozapine concentrations in humans from a scaled pharmacokinetic model for rat brain and plasma pharmacokinetics Simulated clozapine human unbound concentrations vs. published human concentrations at steady state in plasma with 200, 300 and 400Â mg OID from 10 to 24Â hours. The shape represents the 90% predicted interval of the median and the dots represent the observed data.Back to article page