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Figure 5 | Journal of Translational Medicine

Figure 5

From: Prediction of brain clozapine and norclozapine concentrations in humans from a scaled pharmacokinetic model for rat brain and plasma pharmacokinetics

Figure 5

Visual predictive checks of norclozapine in plasma and brain. Visual predictive check of norclozapine concentrations in plasma (A) and brain (B) following a 10 mg/kg subcutaneous dose of norclozapine. Dashed line is the median of observed concentrations, the shape represents the 90% predicted interval of the median, and the dots represent the observed concentrations.

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