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Figure 3 | Journal of Translational Medicine

Figure 3

From: Prediction of brain clozapine and norclozapine concentrations in humans from a scaled pharmacokinetic model for rat brain and plasma pharmacokinetics

Figure 3

Model diagnostic plots for norclozapine. A and E: population prediction vs. observation plots for norclozapine in plasma and brain ECF, respectively, dashed line is the line of identity. B and F: individual prediction vs. observation plots for norclozapine in plasma and brain ECF, respectively. C and G: conditional weighted residuals vs. time for norclozapine in plasma and brain ECF, respectively. D and H: conditional weighted residuals vs. population prediction for norclozapine in plasma and brain ECF, respectively.

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