Figure 2

Model diagnostic plots for clozapine. A and E: population prediction vs. observation plots for clozapine in plasma and brain ECF, respectively, solid line is line of identity. B and F: individual prediction vs. observation plots for clozapine in plasma and brain ECF, respectively. C and G: conditional weighted residuals vs. time for clozapine in plasma and brain ECF, respectively. D and H: conditional weighted residuals vs. population prediction for clozapine in plasma and brain ECF, respectively.