Table 3 Comparison of mouse immune-related protein profiling in PC14PE6-RFP-derived tumors at day seven after treatment begin (n = 3)
Antigen names | Ratios a | Classification |
|---|---|---|
(A) GLV-1h68/PBS | ||
Eotaxin | 9.34* | Proinflammatory chemokine |
Interleukin-11 (IL-11) | 1.90* | Cytokine |
Interleukin-2 (IL-2) | 1.97* | Cytokine |
Interleukin-7 (IL-7) | 1.63* | Proinflammatory cytokine |
Macrophage Inflammatory Protein-1 beta (MIP-1 beta) | 3.76* | Proinflammatory chemokine |
Monocyte Chemotactic Protein 1 (MCP-1) | 18.30** | Proinflammatory chemokine |
Monocyte Chemotactic Protein 3 (MCP-3) | 11.12** | Proinflammatory chemokine |
Monocyte Chemotactic Protein-5 (MCP-5) | 27.85* | Proinflammatory chemokine |
Myeloperoxidase (MPO) | 3.99** | Peroxidase enzyme |
Oncostatin-M (OSM) | 1.99* | Cytokine |
Tumor Necrosis Factor alpha (TNF-alpha) | 2.05* | Proinflammatory cytokine |
Epidermal Growth Factor Mouse (EGF Mouse) | 0.54* | Growth factor |
(B) GLV-1h68 + CPA/ PBS |  |  |
Macrophage Colony-Stimulating Factor-1 (M-CSF-1) | 1.69* | Proinflammatory cytokine |
Monocyte Chemotactic Protein 1 (MCP-1) | 20.16* | Proinflammatory chemokine |
Monocyte Chemotactic Protein-5 (MCP-5) | 30.60* | Proinflammatory chemokine |
Apolipoprotein A-I (Apo A-I) | 0.17* | Anti-inflammatory protein |
Epidermal Growth Factor Mouse (EGF Mouse) | 0.54* | Growth factor |
Fibrinogen | 0.52* | Blood coagulation |
Vascular Cell Adhesion Molecule-1 (VCAM-1) | 0.45* | Cell-cell adhesion |
von Willebrand factor (vWF) | 0.39* | Blood coagulation |
(C) GLV-1h68/CPA | Â | Â |
Eotaxin | 12.43* | Proinflammatory chemokine |
Granulocyte Chemotactic Protein-2 Mouse (GCP-2 Mouse) | 2.51* | Proinflammatory chemokine |
Growth-Regulated Alpha Protein (KC/GRO) | 2.96* | Proinflammatory chemokine |
Interleukin-10 (IL-10) | 2.74* | Cytokine |
Interleukin-12 Subunit p70 (IL-12p70) | 2.11* | Pleiotropic cytokine |
Macrophage Inflammatory Protein-1 beta (MIP-1 beta) | 3.06* | Proinflammatory chemokine |
Macrophage Inflammatory Protein-3 beta (MIP-3 beta) | 2.90** | Proinflammatory chemokine |
Matrix Metalloproteinase-9 (MMP-9) | 2.30* | Enzyme |
Monocyte Chemotactic Protein 1 (MCP-1) | 9.76** | Proinflammatory chemokine |
Monocyte Chemotactic Protein 3 (MCP-3) | 5.90** | Proinflammatory chemokine |
Monocyte Chemotactic Protein-5 (MCP-5) | 20.97* | Proinflammatory chemokine |
(D) GLV-1h68 + CPA/CPA |  |  |
Granulocyte Chemotactic Protein-2 Mouse (GCP-2 Mouse) | 3.05* | Proinflammatory chemokine |
Interleukin-6 (IL-6) | 5.01* | Cytokine |
Monocyte Chemotactic Protein 1 (MCP-1) | 10.75* | Proinflammatory chemokine |
Monocyte Chemotactic Protein-5 (MCP-5) | 23.04* | Proinflammatory chemokine |
Serum Amyloid P-Component (SAP) | 1.38* | Acute phase reactant |
T-Cell-Specific Protein RANTES (RANTES) | 3.32* | Proinflammatory chemokine |
Tissue Inhibitor of Metalloproteinases 1 Mouse (TIMP-1 Mouse) | 2.56* | Protein inhibitor |
Vascular Cell Adhesion Molecule-1 (VCAM-1) | 0.78* | Cell-cell adhesion |
(E) CPA/PBS | Â | Â |
von Willebrand factor (vWF) | 0.48* | Blood coagulation |
(F) GLV-1h68 + CPA/GLV-1h68 |  |  |
von Willebrand factor (vWF) | 0.55** | Blood coagulation |