Figure 4

Imaging of live animals. Mice were imaged at 14 (A) or 21 (B) days post initiation of treatment. The images show the tumor area of four representative mice of each group. At the left side of each unit an overlay of white light images of the mice and fluorescence images (RFP: tumor; GFP: infection) are shown. On the top right side separate RFP signals respectively on the bottom right GFP signals are displayed. (C) Quantification of tumor burden (RFP signals) and viral infection (GFP signals) by scaled counts/s. (D) Calculation of the percent of infected tumor area.