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Figure 3 | Journal of Translational Medicine

Figure 3

From: Roles of CXCL5 on migration and invasion of liver cancer cells

Figure 3

Chemotaxis of recombinant CXCL5 on LCCs and Specificity of CXCL5/CXCR2. A: Effect of recombinant CXCL5 on the migration and invasion of HepG2 measured by transwell assay (×200); (B) Average cell numbers of migration and invasion in three identical experiments (n = 3 each), HepG2 cells were incubated at the upper chamber and recombinant CXCL5 (0.1, 1.0, or 10 nM) was added into the lower compartment; (C) Effect of CXCR2 inhibitor SB225002 on CXCL5-induced migration and invasion of HepG2 measured by transwell (×200); (D) Average cell numbers of migration and invasion in three identical experiments (n = 3 each). (E) Effect of SB225002 on CXCL5-induced migration and invasion of HepG2 measured by wound-healing assay (×100); (F) Levels of healing percent. (*P < 0.05, **P < 0.01, ***P < 0.001, ++P < 0.01, +++P < 0.001).

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