Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma

Table 3 Relationship between soluble CD147 and variable clinicopathologic features

Clinicopathologic features	n = 50	Soluble CD147		P value
Clinicopathologic features	n = 50	Range (ng/ml)	Median (ng/ml)	P value
Child-Pugh grade				0.007
A	37	2.218–19.890	4.308
B	13	3.306–20.820	5.727
Tumor number				0.470
Single	28	2.727–19.890	4.427
Multiple	22	2.218–20.820	5.232
Tumor size (cm)				0.007
<3	24	2.818–6.382	4.301
3–5	17	2.218–20.820	4.308
≥5	9	4.484–12.370	5.845
BCLC stage				0.195
0	12	2.973–6.220	3.991
A	19	2.727–19.890	4.482
B	13	2.218–20.820	4.909
C^#	6	3.745–12.370	6.359

^#Significant difference as compared with BCLC 0 group (P = 0.044). BCLC denotes Barcelona Clinic Liver Cancer Staging System.

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