Table 1 Cardiac function at baseline and after 20 minutes exposure to hypoxic stimulus

Cardiac output (L/min)

6.0 ± 1.2

8.1 ± 1.6***

Ejection fraction (%)

67 ± 4

75 ± 6***

RV ED diameter (mm)

25 ± 4

26 ± 3

RA diameter (mm)

20 ± 4

19 ± 2

LA diameter (mm)

39 ± 4

38 ± 3

PA blood flow velocity (m/s)

0.8 ± 0.1

1.0 ± 0.1*

Vena cava inferior (mm)

16.8 ± 4.6

15.2 ± 4.2

RV-to-RA pressure gradient (mmHg)

28 ± 5

31 ± 3*

RV E’/ A’ (cm/s)

1.5 ± 0.4

1.4 ± 0.2

RV S_m (cm/s)

0.20 ± 0.04

0.24 ± 0.04*

Pulmonary vein s/d ratio

1.3 ± 0.2

1.4 ± 0.3

TAPSE (cm)

2.6 ± 0.2

3.0 ± 0.3**

LAD diameter (cm)

5.62 ± 0.64

5.60 ± 0.64

LAD blood flow velocity (m/s)

0.16 ± 0.4

0.28 ± 0.07**

LV lateral wall E’/A’

1.9 ± 0.7

1.5 ± 0.6

LV septal wall E’/A’

1.6 ± 0.3

1.5 ± 0.3

LV septum S_m (cm/s)

0.12 ± 0.02

0.15 ± 0.05

LV lateral wall S_m (cm/s)

0.16 ± 0.06

0.19 ± 0.06

Lateral mitral annular displacement (cm)

1.5 ± 0.2

1.8 ± 0.2**

Septal mitral annular displacement (cm)

1.5 ± 0.1

1.7 ± 0.3*

E/A –ratio

1.6 ± 0.3

1.4 ± 0.2*