Age diet | 12 SD‡(n = 8) | 12 HFSD (n = 8) | 24 HFSD (n = 8) | 48 HFSD (n = 8) |
|---|
NAS§
| 0.00 ± 0.00 |
3.20 ± 0.49*
|
7.33 ± 0.33*
|
6.83 ± 0.31*
|
Fibrosis | 0.00 ± 0.00 | 0.02 ± 0.20 |
2.00 ± 0.00*
|
2.42 ± 0.08*
,
**
|
- Data are expressed as mean ± standard of error (SE).
-
†HFSD, high fat and sucrose diet.
-
‡SD, standard chow is considered as standard diet
- §NAS, nonalcoholic fatty liver disease activity score, which is the summation of the pathologic scores for steatosis, inflammation and hepatic ballooning.
- *P < 0.05, when compared with mice given HFSD.
- **P < 0.05, when compared with mice given HFSD for 24 weeks.
- Results with statistical significances are shown in bold letters.
