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Table 1 T-Test P-values comparing DDR readouts between BRCA1 +/- vs. BRCA1 +/+ cell lines

From: Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP)

Treatment AZD AZD AZD + TMZ AZD + TMZ
Timepoint: 48 h 72 h 48 h 72 h
Population: All cells Cyclin A2- Cyclin A2+ All cells Cyclin A2- Cyclin A2+ All cells Cyclin A2- Cyclin A2+ All cells Cyclin A2- Cyclin A2+
Stain:             
p-H2AX 0.536 0.119 0.012 0.558 0.151 0.039 0.673 0.172 0.014 0.509 0.272 0.011
p-RPA2 0.545 0.372 0.545 0.599 0.442 0.229 0.875 0.445 0.916 0.900 0.767 0.859
p-DNA-PKcs 0.398 0.419 0.957 0.597 0.469 0.336 0.776 0.952 0.894 0.758 0.562 0.297
p21 0.315 0.413 0.132 0.645 0.737 0.203 0.693 0.708 0.364 0.778 0.706 0.452
p-ATM 0.636 0.848 0.390 0.940 0.693 0.228 0.746 0.967 0.736 0.813 0.920 0.694
p-BRCA1 0.754 0.954 0.608 0.505 0.872 0.721 0.858 0.839 0.756 0.684 0.970 0.860
  1. Statistically significant p-values (p < .05) for stratifying BRCA1+/- vs. BRCA1+/+cell lines are shown in bold.