Table 2 Genes up regulated in HL-60 cells treated with PLVX-MT-3 compared with control group

1

FOXO1

forkhead box O1

26.4281

331.0229

12.5254

0.010474

2

IER3

immediate early response 3

452.3756

4374.4713

9.6700

0.010816

3

CD5

CD5 molecule

0.6702

6.2407

9.3121

0.010872

4

NDUFS3

NADH dehydrogenase (ubiquinone) Fe-S protein 3

1081.0850

9828.4023

9.0912

0.010909

5

TNFAIP3

tumor necrosis factor, alpha-induced protein 3

587.6202

4806.8271

8.1802

0.011077

6

TNF

tumor necrosis factor

0.4428

3.4995

7.9040

0.011134

7

DDIT3

DNA-damage-inducible transcript 3

1145.0392

8216.9381

7.1761

0.011304

8

CRADD

CASP2 and RIPK1 domain containing adaptor with death domain

86.0764

598.6941

6.9554

0.011361

9

BNIP1

BCL2/adenovirus E1B 19 kDa interacting protein 1

763.0465

5084.0947

6.6629

0.011443

10

BBC3

BCL2 binding component 3

11.7979

73.7195

6.2486

0.01157

11

NOX5

NADPH oxidase, EF-hand calcium binding domain 5

1.8139

11.2984

6.2286

0.011576

12

CASP7

caspase 7, apoptosis-related cysteine peptidase

172.3255

1016.9670

5.9014

0.011688

13

PIM2

pim-2 oncogene

247.2885

1270.8713

5.1392

0.012

14

CEBPG

CCAAT/enhancer binding protein (C/EBP), gamma

100.8660

510.3751

5.0599

0.012038

15

EDA

ectodysplasin A

6.0342

30.4256

5.0422

0.012047

16

SOCS2

suppressor of cytokine signaling 2

2.1896

10.8844

4.9710

0.012082

17

CDKN1A

cyclin-dependent kinase inhibitor 1A

1057.6600

5124.4420

4.8451

0.012147