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Figure 4 | Journal of Translational Medicine

Figure 4

From: Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway

Figure 4

C1/C1q binding at therapeutic hypothermia temperatures. C1q binding was tested by incubating antibody-sensitized erythrocytes with (A) purified C1q, (B) normal human serum, or (C) C8-deficient serum for one hour at 31-41°C. In each case, there was a consistent trend of increased C1q binding to EA at lower temperatures. Data are mean ± SEM for 4 independent experiments.

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