ALIP-like clusters during CR in AML patients were considered the best indicator of early relapse among the three precursor group. (A) Densities of single, double, and clustered precursors were higher in the pre-relapse cases. (B) showing ROC analysis for the prediction of relapse from single, double and clustered precursors. This analysis showed that ALIP-like clusters mostly favored the prediction of relapse with AUC = 0.711. AUC: Area under curve. (C) The median time from histologic relapse to overt hematologic relapse.