| All n = 210 | GG n = 146 | GC/CC n = 64 | p value |
---|---|---|---|---|
Age [years] | 63 ± 15 | 63 ± 16 | 63 ± 15 | 0.9116 |
Male, % | 64% | 46% | 58% | 0.2752 |
Body-mass index, mean ± SD | 28 ± 9 | 28 ± 7 | 30 ± 13 | 0.1507 |
Severity of sepsis | 48% | 46% | 52% | 0.4576 |
Sepsis/severe sepsis, % | 52% | 54% | 48% | Â |
Septic shock, % | Â | Â | Â | |
SOFA score, mean ± SD | 8.6 ± 4.1 | 8.9 ± 4.3 | 8.0 ± 3.7 | 0.2449 |
APACHE II score, mean ± SD | 21.3 ± 7.4 | 21.6 ± 7.4 | 20.6 ± 7.6 | 0.4053 |
Comorbidities, % | Â | Â | Â | Â |
Hypertension | Â | 58 | 59 | 1.0000 |
History of myocardial infarction | Â | 5 | 6 | 0.7586 |
COPD | Â | 18 | 17 | 1.0000 |
Renal dysfunction | Â | 11 | 20 | 0.0834 |
Diabetes mellitus (NIDDM) | Â | 11 | 8 | 0.6202 |
Diabetes mellitus (IDDM) | Â | 11 | 5 | 0.1938 |
Chronic liver diseases | Â | 7 | 9 | 0.7839 |
History of cancer | Â | 18 | 19 | 0.8481 |
History of stroke | Â | 6 | 8 | 0.7647 |
Recent surgical history, % | Â | Â | Â | 0.0631 |
Elective surgery | 28 | 31 | 19 | Â |
Emergency surgery | 44 | 44 | 44 | Â |
No history of surgery | 28 | 24 | 37 | Â |
Site of infection, % | Â | Â | Â | 0.1516 |
Lung | 50 | 46 | 56 | Â |
Abdomen | 30 | 31 | 28 | Â |
Bone or soft tissue | 7 | 7 | 6 | Â |
Surgical wound | 2 | 3 | 0 | Â |
Urogenital | 1 | 0 | 3 | Â |
Primary bacteremia | 6 | 7 | 3 | Â |
Other | 4 | 5 | 3 | Â |
Organ support, % | Â | Â | Â | Â |
Mechanical ventilation | 83 | 83 | 83 | 0.8933 |
Use of vasopressor | 52 | 54 | 48 | 0.4576 |
Renal-replacement therapy | 10 | 11 | 9 | 0.7300 |