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Figure 1 | Journal of Translational Medicine

Figure 1

From: Gene expression identifies heterogeneity of metastatic behavior among high-grade non-translocation associated soft tissue sarcomas

Figure 1

Top: clustering of gene expression in the 309 high-grade STS samples using the Eisen clustering software Cluster. The samples were clustered by complete-linkage hierarchical clustering with uncentered correlation using the Eisen clustering software Cluster and the 533 probes present in the pooled gene set as described in the text. Groups A and B are defined by the first branch point in the clustering. Groups 1–4 are defined by the second branch points. Middle and bottom: Kaplan-Meier analysis of the time to development of metastases of the two groups (groups A and B) and four groups (groups 1–4), defined by the first and second break points, respectively, of the hierarchical clustering. The time to development of metastasis differed between groups A and B (p = 0.048), and groups 1–4 (p < 0.0001) (see Additional file 1: Table S1).

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