Skip to main content

Table 3 Comparison between the clinically good and poor responders

From: Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable pancreatic cancer

Characteristics

Clinically good (CR/PR/SD)

Clinically poor (PD)

p-value

Number of patients

26

16

 

Age (years)

61.6 (37-81)

65.6 (43-81)

p = 0.2434

Sex

  

p = 0.7513

 Males

12

9

 

 Females

14

7

 

Stage

  

p = 0.0735

 III

12

2

 

 IV

9

10

 

 Recurrence

5

4

 

Liver metastasis (pretreatment)

  

p = 0.0081

 Absence

25

10

 

 Presence

1

6

 

NLR

2.3 (0.7-6.4)

3.1 (0.4-6.1)

p = 0.1364

Number of CTLs (x108/time)

7.0 (2.8-12.4)

5.1 (1.0-9.0)

p = 0.0537

Number of DCs (x107/time)

2.1 (0.9-3.9)

1.2 (0.04-2.9)

p = 0.0015

  1. CR; complete response, PR; partial response, SD; stable disease, PD; progressive disease NLR; neutrophil/lymphocyte ratio, CTL; cytotoxic T lymphocyte, DC; dendritic cell.