Skip to main content

Advertisement

Table 3 Concordances between single methods and combined gene/protein methods

From: The validation of a novel method combining both HER2 immunohistochemistry and HER2 dual-colour silver in situ hybridization on one slide for gastric carcinoma testing

Single vs. combination Concordance Kappa-Coefficient к Agreement Altmann [[15]]
SISH amplified 100 % 1 Very good
IHC score 0 100 % 1 Very good
IHC score 1+ 98.96% 0.947 Very good
IHC score 2+ 95.83% 0.728 Good
IHC score 3+ 96.88% 0.825 Very good
  1. Abbreviations: IHC immunohistochemistry, SISH silver in situ hybridization.