From: The validation of a novel method combining both HER2 immunohistochemistry and HER2 dual-colour silver in situ hybridization on one slide for gastric carcinoma testing
Single vs. combination
Concordance
Kappa-Coefficient к
Agreement Altmann [[15]]
SISH amplified
100 %
1
Very good
IHC score 0
IHC score 1+
98.96%
0.947
IHC score 2+
95.83%
0.728
Good
IHC score 3+
96.88%
0.825