Figure 2From: The therapeutic target of estrogen receptor-alpha36 in estrogen-dependent tumors Diagram of locations of different ERs. ER-α36 is mainly localized in plasma membrane and cytoplasm, little is found in nucleus. Classical ERs like ER-α66 and ER-β are mainly expressed in nucleus and cytoplasm with little in plasma membrane. As to other ERs (e.g. ER-α46 and GPER), the cellular localization usually depends on cell types.Back to article page