Telomere length and the correlations thereof with stathmin and elongation factor 1α (EF1α) expression in HBV-related multistep hepatocarcinogenesis. A. Telomere terminal restriction fragment (TRF) length in normal liver (NL), liver cirrhosis (LC), low-grade dysplastic nodules (LGDN), high-grade dysplastic nodules (HGDN), and hepatocellular carcinoma (HCC). B-C. Correlation between TRF length and stathmin mRNA (B) and stathmin protein levels (C). D. Correlation between TRF length and EF1α protein levels. ‡ Statistical significance (linear trend model, P < 0.05). *Statistical significance (P < 0.05).