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Table 1 The predicted top ten combinations of drugs for the treatment of type 2 diabetes

From: Drug-repurposing identified the combination of Trolox C and Cytisine for the treatment of type 2 diabetes

Drug 1

Drug 2

m1

n1

m2

n2

Score

Trifluridine

Trolox C

22

8

61

24

518

Thiethylperazine

Trolox C

17

6

63

17

506

Cytisine

Trolox C

15

6

60

8

468

Cytisine

Ozagrel

23

8

48

20

420

Prenylamine

Thiethylperazine

17

1

42

16

416

Paclitaxel

Trolox C

12

4

61

10

408

Vinburnine

Trolox C

18

4

53

24

406

Ozagrel

Paclitaxel

22

7

47

20

405

Cytisine

Vancomycin

18

7

59

23

396

Valproic acid

Trifluridine

20

9

60

24

396

  1. m1-the number of reversed genes by drug 1.
  2. n1-the number of genes induced to the same deregulation as type 2 diabetes by drug 1.
  3. M2-the number of reversed genes by drug 2.
  4. n2-the number of genes induced to the same deregulation as type 2 diabetes by drug 2.