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Figure 2 | Journal of Translational Medicine

Figure 2

From: Synergic silencing of costimulatory molecules prevents cardiac allograft rejection

Figure 2

CD40 and CD80 gene silencing in vivo . Fifty micrograms of CD40 and CD80 siRNA vector or scrambled siRNA control vector were administrated to mice by iv injection. Forty-eight hours after injection, 0.5 mg LPS was administrated by ip injection. Splenic DCs were isolated 24h after LPS injection using MACS beads. Scrambled siRNA vector treated mice served as a control. The expression of CD40 and CD80 in splenic DCs was detected by flow cytometry.

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