Figure 6From: Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion LDH activity and infarct size in hearts in Experimental Series 2. The experiments were carried out on Control (n = 9), Iso/Ade (n = 9), cyclosporine A (CsA, n = 6) and Iso/Ade + CsA (n = 8) groups of hearts. The perfusion protocol of Iso/Ade group in this series of experiments was similar to that of Iso/Ade-0 group in Experimental Series 1. Panel A – LDH activity in the effluent perfusate during 30 min reperfusion. Differences between control and three other groups (measured for the corresponding data points) were statistically significant (P < 0.05) at all data points. There was no significant difference in LDH activity between the three intervention groups. Panel B – Infarct size. Mean ± SEM (columns) and representative images of the corresponding heart slices stained with TTC. ** P < 0.01, *** P < 0.001 vs. Control.Back to article page