LDH activity and infarct size in hearts in Experimental Series 2. The experiments were carried out on Control (n = 9), Iso/Ade (n = 9), cyclosporine A (CsA, n = 6) and Iso/Ade + CsA (n = 8) groups of hearts. The perfusion protocol of Iso/Ade group in this series of experiments was similar to that of Iso/Ade-0 group in Experimental Series 1. Panel A – LDH activity in the effluent perfusate during 30 min reperfusion. Differences between control and three other groups (measured for the corresponding data points) were statistically significant (P < 0.05) at all data points. There was no significant difference in LDH activity between the three intervention groups. Panel B – Infarct size. Mean ± SEM (columns) and representative images of the corresponding heart slices stained with TTC. ** P < 0.01, *** P < 0.001 vs. Control.