Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer

Table 2 Univariate and multivariate analyses of PFS in patients with epithelial ovarian cancer

Variables	Categories	Univariate analysis		P	Multivariate analysis		P
Variables	Categories	HR^a	95% CI^b	P	HR^a	95% CI^b	P
Age	<60
	≥60	1.061	0.744-1.512	0.744	—	—	—
FIGO stage	I + II
	III + IV	2.081	1.371-3.159	0.001*	1.789	1.170-2.733	0.007*
Grade	G1
	G2	0.909	0.523-1.581	0.735	—	—	—
	G3	1.291	0.789-2.113	0.309	—	—	—
Histological type	Serous
	Nonserous	1.059	0.750-1.496	0.744	—	—	—
Lymph node metastasis	Negative
	Positive	2.988	2.028-4.403	<0.001*	2.308	1.531-3.480	<0.001*
FOXM1	Negative
	Positive	1.878	1.292-2.729	0.001*	1.494	1.007-2.215	0.046*

PFS progression-free survival, ^a HR = hazard ratio, ^b CI = confidence interval, *P < 0.05.

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