NGF improves the locomotor activity of SCI rats. A. The BBB scores and B. incline plane test of sham, SCI group and SCI rat treated with NGF group. * P < 0.05 versus the SCI group, and ** P < 0.01 versus the SCI group, n = 6. C. Representative footprints obtained from each group at 14 days after SCI show that NGF treated rats display fairly consistent weight-support plantar stepping and very little toe dragging. In contrast, vehicle control rats show consistent dorsal stepping and extensive toe dragging.