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Table 2 AUC of IgG and IgM antibodies against pre-diagnostic antigens

From: Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer

Antigens

IgG

IgM

IgG + IgM

 

Pre-diagnostic

Tumor bearing

Pre-diagnostic

Tumor bearing

Pre-diagnostic

Tumor bearing

Phdx

0.507

0.507

0.500

0.500

0.507

0.507

Otud6b

0.784

0.784

0.782

0.574

0.818

0.658

Stk39

0.640

0.640

0.582

0.547

0.704

0.591

Lgals8

0.781

0.813

0.732

0.574

0.737

0.593

Vps35

0.500

0.500

0.503

0.500

0.508

0.500

Znf238

0.522

0.548

0.661

0.541

0.648

0.534

Otud6b + Stk39 + Lgals8

0.868

0.871

0.841

0.676

0.924

0.676