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Table 1 Pre-diagnostic antigens identified using SEREX

From: Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer

Genes

Full gene name

SubcellularLocation

Homology

Phdx

Pyruvate dehydrogenase complex

Mitochondria

89%

Otud6b

OTU domain containing 6B

Cytoplasm and Nucleus

95%

Stk39

Serine/threonine kinase 39 (STE20/SPS1 homolog, yeast)

Cytoplasm and Nucleus

94%

Zfp238

Zinc finger protein 238

Nucleus

100%

Lgals8

Lectin, galactoside-binging, soluble,8

Cytoplasm

80%

Vps35

Vacuolar protein sorting 35

Cytoplasm

99%