Figure 2From: Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer IgM antibodies to pre-diagnostic antigens are more commonly identified in sera from mice prior to the development of palpable breast cancer. Incidence of IgG (black bar) and IgM (white bar) for antigen Pdhx, Otud6b, Stk39, Lgals8, Znf238 and Vps35 in sera obtained (A) pre-diagnosis or when (B) tumor bearing. Incidence of IgG (black bar) and IgM (white bar) antibody detection for a panel with any 1 antigen, 2 antigens, 3 antigens and 4 antigens in sera obtained (C) pre-diagnosis or when (D) tumor bearing.Back to article page