Skip to main content

Table 3 Distribution of somatic alterations in multiple melanomas from our series

From: Discrepant alterations in main candidate genes among multiple primary melanomas

Sample

Frequency of alterations, positive/total samples (%)

BRAF mutation

cKIT amplification

CyclinD1 amplification

All melanomas

109/229 (47.6)

10/216 (4.6)

29/214 (13.6)

First melanoma

50/107 (46.7)

2/101 (2.0)

7/100 (7.0)

Second melanoma

52/107 (48.6)

6/101 (5.9)

21/100 (21.0)

Third/Fourth melanoma

7/15 (46.7)

2/14 (14.3)

1/14 (7.1)