From: Discrepant alterations in main candidate genes among multiple primary melanomas
Sample | Frequency of alterations, positive/total samples (%) | ||
---|---|---|---|
BRAF mutation | cKIT amplification | CyclinD1 amplification | |
All melanomas | 109/229 (47.6) | 10/216 (4.6) | 29/214 (13.6) |
First melanoma | 50/107 (46.7) | 2/101 (2.0) | 7/100 (7.0) |
Second melanoma | 52/107 (48.6) | 6/101 (5.9) | 21/100 (21.0) |
Third/Fourth melanoma | 7/15 (46.7) | 2/14 (14.3) | 1/14 (7.1) |