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Table 6 Highly conserved epitopes from E2 of 3a and 1a

From: De Novo modeling of Envelope 2 protein of HCV isolated from Pakistani patient and epitopes prediction for vaccine development

Epitopes

B-cell/T-cell

PVYCFTPSPVVV

B-cell

TPSPVVVGT

T-cell (HLA-B_3501, HLA-B_5101, HLA-B_5102, HLA-B_5103, MHC-Ld)

VYCFTPSPV

T-cell (DRB1_0102, DRB1_0423, DRB1_1501, DRB1_1506)

FTPSPVVVG

T-cell (DRB1_0309, DRB1_0421)

YCFTPSPVV

T-cell (DRB1_0701, DRB1_0703)

YRLWHYPCT

T-cell (DRB1_1502, DRB1_1506)