Table 1 Histological score of tendon repair
From: Efficacy of a mesenchymal stem cell loaded surgical mesh for tendon repair in rats
Score | Collagen | Angiogenesis | Cellularity |
|---|---|---|---|
0 | dense, clearly defined parallel collagen bundles oriented tangentally | a sparse network of small arteries oriented parallel to the collagen fibers in thin, fibrous septa between the bundles | fairly even, sparse distribution of cells with thin wavy nuclei located between collagen bundles |
1 | less than 25% of collagen bundles have a diffuse structure with blurring of individual bundles | less than 25% irregular vascularization: increased capillaries | less than 25% abnormal increased cellularity with rounded nuclei oriented in rows |
2 | less than 50% of collagen bundles have a diffuse structure with blurring of individual bundles | less than 50% irregular vascularization: increased capillaries; groups of thick-walled vessels distributed unevenly in the hypercellular tendon | less than 50% abnormal increased cellularity with rounded nuclei oriented in rows |
3 | more than 50% of collagen bundles have a diffuse structure with blurring of individual bundles | more than 50% irregular vascularization: increased capillaries; groups of thick-walled vessels distributed unevenly in the hypercellular tendon; proliferating vessels are nodular and may be perpendicular to the collagen bundles | more than 50% abnormal increased cellularity with rounded nuclei oriented in rows |