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Table 6 Semiquantitive analysis of WB of Paeonol on HCT116 and SW480

From: ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition

 

0 mM/L

0.2 mM/L

0.4 mM/L

β-catenin-H

0.38 ± 0.04

0.22 ± 0.03*

0.13 ± 0.04*

Cox2-H

0.17 ± 0.07

0.04 ± 0.008#

0.01 ± 0.002*

p53-H

0.35 ± 0.14

0.17 ± 0.07#

0.08 ± 0.04*

PCNA-H

0.37 ± 0.09

0.19 ± 0.08#

0.09 ± 0.04*

β-catenin-S

0.21 ± 0.03

0.13 ± 0.04#

0.05 ± 0.03*

Cox2-S

0.14 ± 0.04

0.05 ± 0.01*

0.008 ± 0.002*

p53-S

0.48 ± 0.18

0.20 ± 0.08#

0.10 ± 0.05*

PCNA-S

0.22 ± 0.04

0.12 ± 0.04#

0.08 ± 0.06#

E-cadherin-SS

0.04 ± 0.03

0.23 ± 0.06*

0.35 ± 0.08*

N-cadherin-SS

0.42 ± 0.06

0.30 ± 0.08#

0.15 ± 0.03*

Vimentin-SS

0.37 ± 0.05

0.18 ± 0.05*

0.07 ± 0.04*

  1. *: P < 0.01 VS 0; #: P < 0.05 VS 0; H: HCT116; S: SW480; SS: SW480 with Snail overexpression.