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Table 5 Semiquantitive analysis of WB of SYD on HCT116 and SW480

From: ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition

 

0 mg/mL

2 mg/mL

4 mg/mL

β-catenin-H

0.61 ± 0.03

0.33 ± 0.06*

0.193 ± 0.07*

Cox2-H

0.24 ± 0.03

0.13 ± 0.03*

0.09 ± 0.03*

p53-H

0.52 ± 0.06

0.35 ± 0.06#

0.19 ± 0.06*

PCNA-H

0.32 ± 0.06

0.17 ± 0.08#

0.11 ± 0.04*

β-catenin-S

0.68 ± 0.009

0.34 ± 0.06*

0.28 ± 0.02*

Cox2-S

0.08 ± 0.01

0.02 ± 0.01*

0.008 ± 0.001*

p53-S

0.55 ± 0.10

0.34 ± 0.08#

0.25 ± 0.09*

PCNA-S

0.32 ± 0.12

0.09 ± 0.06#

0.06 ± 0.03*

E-cadherin-SS

0.09 ± 0.03

0.30 ± 0.08#

0.51 ± 0.12*

N-cadherin-SS

0.22 ± 0.05

0.09 ± 0.02*

0.06 ± 0.02*

Vimentin-SS

0.53 ± 0.06

0.35 ± 0.07#

0.15 ±0.07*

  1. *: P < 0.01 VS 0; #: P < 0.05 VS 0; H: HCT116; S: SW480; SS: SW480 with Snail overexpression.