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Table 4 Semiquantitive analysis of IHC and WB

From: ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition

 

Control

Model

SYD

β-catenin-IHC

0.52 ± 0.39

4.12 ± 1.83 △

2.23 ± 1.92 #

Cox2-IHC

0.97 ± 0.30

6.18 ± 2.02△

3.06 ± 1.53*

p53-IHC

0.66 ± 0.45

6.03 ± 2.17△

3.33 ± 2.07#

PCNA-IHC

1.26 ± 0.60

5.63 ± 2.21△

3.06 ± 1.95#

E-cadherin-IHC

0.50 ± 0.39

0.09 ± 0.07

3.44 ± 1.69#

N-cadherin-IHC

0.51 ± 0.38

8.10 ± 1.52△

4.22 ± 1.19#

Fibronectin-IHC

0.80 ± 0.81

7.48 ± 2.08△

4.14 ± 1.59#

Vimentin-IHC

0.24 ± 0.28

4.92 ± 1.73△

2.84 ± 1.46#

NF-κB-IHC

0.89 ± 0.48

8.29 ± 1.53△

4.69 ± 1.83#

F4/80-IHC

0.03 ± 0.04

6.05 ± 1.61△

3.89 ± 1.54#

β-catenin-WB

0.008 ± 0.006

0.750 ± 0.292△

0.250 ± 0.270#

Cox2-WB

0.277 ± 0.070

0.677 ± 0.239▲

0.307 ± 0.074#

p53-WB

0.064 ± 0.040

0.370 ± 0.105△

0.165 ± 0.073#

PCNA-WB

0.089 ± 0.0226

0.282 ± 0.091△

0.158 ± 0.039#

E-cadherin-WB

0.723 ± 0.229

0.194 ± 0.099▲

0.560 ± 0.185#

N-cadherin-WB

0.096 ± 0.055

0.620 ± 0.271▲

0.262 ± 0.131#

Vimentin-WB

0.217 ± 0.038

0.583 ± 0.200▲

0.290 ± 0.110#

Snail-WB

0.085 ± 0.037

0.423 ± 0.146△

0.187 ± 0.096#

Claudin-1-WB

0.018 ± 0.017

0.280 ± 0.141△

0.109 ± 0.027#

  1. *: P < 0.01 VS Model; #: P < 0.05 VS Model.
  2. △: P < 0.01 VS Control; ▲: P < 0.05 VS Control.
  3. IHC: Immunohistochemistry; WB: Western blot.