Figure 2

Effects of SYD on the burden of colonic neoplasms. (A) Microscopic view of colon in mice. (B) Effect of SYD on colonic neoplasm size. SYD significantly suppressed tumor growth and reduced neoplasm size. Data are presented as mean ± SD. *P < 0.01 vs. model, # P < 0.05 vs. model. (C) Effects of SYD on tumour weight and tumour volume in each mice. SYD significantly decreased tumour weight and tumour volume. (D) Most colorectal neoplasms were histologically consistent with tubular adenoma or adenocarcinoma. Histological studies were carried out through hematoxylin and eosin staining as previously described. (Da) Normal colon; (Db) tubular adenoma; (Dc) adenocarcinoma. 40 × for all, scale bar = 100 μm. The analysis of differentiation and invasion is shown in Table 3 (P = 0.041).