TY - JOUR AU - Keller, Betsy A. AU - Pryor, John Luke AU - Giloteaux, Ludovic PY - 2014 DA - 2014/04/23 TI - Inability of myalgic encephalomyelitis/chronic fatigue syndrome patients to reproduce VO2peak indicates functional impairment JO - Journal of Translational Medicine SP - 104 VL - 12 IS - 1 AB - Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multi-system illness characterized, in part, by increased fatigue following minimal exertion, cognitive impairment, poor recovery to physical and other stressors, in addition to other symptoms. Unlike healthy subjects and other diseased populations who reproduce objective physiological measures during repeat cardiopulmonary exercise tests (CPETs), ME/CFS patients have been reported to fail to reproduce results in a second CPET performed one day after an initial CPET. If confirmed, a disparity between a first and second CPET could serve to identify individuals with ME/CFS, would be able to document their extent of disability, and could also provide a physiological basis for prescribing physical activity as well as a metric of functional impairment. SN - 1479-5876 UR - https://doi.org/10.1186/1479-5876-12-104 DO - 10.1186/1479-5876-12-104 ID - Keller2014 ER -