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Table 2 Changes of body weight and plasma lipid profile

From: Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats

 

Con

HFD

HFD + Sim

HFD + BBR

 

(n = 8)

(n = 8)

(n = 8)

(n = 8)

Body weight (g)

325 ± 5.8

405 ± 4.4*

345 ± 9.4#

360 ± 8.7#

TC (mmol/L)

2.20 ± 0.07

2.33 ± 0.12

2.10 ± 0.12#

2.28 ± 0.12

TG (mmol/L)

0.70 ± 0.008

1.80 ± 0.003*

1.20 ± 0.015#

0.80 ± 0.019##

LDL-C (mmol/L)

0.46 ± 0.02

0.93 ± 0.03*

0.56 ± 0.04#

0.52 ± 0.04#

HDL-C (mmol/L)

1.49 ± 0.04

1.10 ± 0.03

1.32 ± 0.10

1.60 ± 0.02##

  1. Con = control; HFD = high fat diet; HFD + Sim = high fat diet + simvastatin; HFD + BBR = high fat diet + berberine; TC = total cholesterol; TG = triglyceride; LDL-C = low density lipoprotein cholesterol; HDL-C = high density lipoprotein cholesterol. *<0.05 vs Con; #<0.05 vs HFD; ##<0.01 vs HFD.
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Journal of Translational Medicine

ISSN: 1479-5876

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