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Table 2 Changes of body weight and plasma lipid profile

From: Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats

  Con HFD HFD + Sim HFD + BBR
  (n = 8) (n = 8) (n = 8) (n = 8)
Body weight (g) 325 ± 5.8 405 ± 4.4* 345 ± 9.4# 360 ± 8.7#
TC (mmol/L) 2.20 ± 0.07 2.33 ± 0.12 2.10 ± 0.12# 2.28 ± 0.12
TG (mmol/L) 0.70 ± 0.008 1.80 ± 0.003* 1.20 ± 0.015# 0.80 ± 0.019##
LDL-C (mmol/L) 0.46 ± 0.02 0.93 ± 0.03* 0.56 ± 0.04# 0.52 ± 0.04#
HDL-C (mmol/L) 1.49 ± 0.04 1.10 ± 0.03 1.32 ± 0.10 1.60 ± 0.02##
  1. Con = control; HFD = high fat diet; HFD + Sim = high fat diet + simvastatin; HFD + BBR = high fat diet + berberine; TC = total cholesterol; TG = triglyceride; LDL-C = low density lipoprotein cholesterol; HDL-C = high density lipoprotein cholesterol. *<0.05 vs Con; #<0.05 vs HFD; ##<0.01 vs HFD.