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Table 3 The distribution of varied CNV in each PI3K/AKT subunits by NanoString nCounter analysis

From: Frequent copy number variations of PI3K/AKT pathway and aberrant protein expressions of PI3K subunits are associated with inferior survival in diffuse large B cell lymphoma

Gene

Total CNV no.

Copy number loss no. (%)

Copy number amplification no. (%)

Total copy number amplification no. (%)

1 copy

3 copy

4 copy

6 copy

PIK3CA

10

0 (0)

9 (90)

1 (10)

0 (0)

10 (100)

PIK3CB

12

0 (0)

11 (92)

1 (8)

0 (0)

12 (100)

PIK3CD

10

7 (70)

2 (20)

1 (10)

0 (0)

0 (30)

PIK3CG

5

1 (20)

4 (80)

0 (0)

0 (0)

4 (80)

PIK3R1

0

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

PIK3R2

14

0 (0)

12 (86)

1 (7)

1 (7)

14 (100)

PIK3C2A

5

1 (20)

4 (80)

0 (0)

0 (0)

4 (80)

PIK3C2B

8

0 (0)

8 (100)

0 (0)

0 (0)

8 (100)

PIK3C2G

12

1 (8)

10 (84)

1 (8)

0 (0)

11 (92)

AKT1

11

4 (36)

6 (55)

1 (9)

0 (0)

7 (64)

AKT2

11

3 (27)

8 (73)

0 (0)

0 (0)

8 (73)

AKT3

13

2 (15)

9 (69)

2 (16)

0 (0)

11 (85)